MV Agusta upgraded its version of the F4, intended to be used as a basis for World Superbike competition, dubbed the F4 Reparto Corse. Only 250 examples were produced. Upon release, this new bike toted 212 horsepower at 13,600 rpm with a Termignoni kit exhaust and ECU installed.
The F4 RC had been significantly changed from the standard F4 and the F4 RR in order to reduce weight by more than 15 pounds. All the engine covers are now manufactured from magnesium, and titanium hardware is used throughout. The pistons, connecting rods and crankshaft have all been redesigned for lighter weight. The radial-valve engine is hand-assembled, and features new intake and exhaust ports. Maximum power in stock trim is claimed to be 205 horsepower.